This third volume of articles dealing with advances in animal welfare science and philosophy covers a wide variety of topics. Major areas of discussion include the ethics and use of animals in biomedical research, farm animal behavior and welfare, and wildlife conservation. Three articles dealing with aspects of equine behavior and welfare cover new ground for this companion species. An in-depth study of the destruction of Latin America's tropical rain forests links the need for conservation and wildlife protection with the devastating impact of the international beef (hamburger) industry, and also highlights serious welfare problems in the husbandry of cattle in the tropics. Papers from a recent symposium at Moorhead State University, Animals and Humans: Ethical Perspectives have been included in this volume. Many of these are "benchmark" papers presenting the most up-to-date and documented evidence in support of animal welfare and rights. Articles oppos ing these position papers are included since they were part of the symposium, and because they provide the reader with a deeper understanding of the arguments given in support of various forms of animal exploitation. While there is no intent to endorse these views by publishing them, it should be acknowledged that without an open and scholarly exchange of opposing of constructive exchange and conflict resolution will views, the possibility remain remote.
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs—replace, reduce, refine—which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines. The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models. This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.
The conservative nature of animal evolution makes animal models the ideal tool for learning about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal Models, Volume II addresses the development and application of models in different areas of biomedical research and details the criteria used to choose animal species and strains. This book is not restricted to laboratory animal models for the study of human diseases. Building on the foundation of the best-selling first edition, the second edition includes many new topics such as animal models in skeletal disease, xenotransplantation, and dental disorders.
The National Institute of Health recently announced its plan to retire the fifty remaining chimpanzees held in national research facilities and place them in sanctuaries. This significant decision comes after a lengthy process of examination and debate about the ethics of animal research. For decades, proponents of such research have argued that the discoveries and benefits for humans far outweigh the costs of the traumatic effects on the animals; but today, even the researchers themselves have come to question the practice. John P. Gluck has been one of the scientists at the forefront of the movement to end research on primates, and in Voracious Science and Vulnerable Animals he tells a vivid, heart-rending, personal story of how he became a vocal activist for animal protection. Gluck begins by taking us inside the laboratory of Harry F. Harlow at the University of Wisconsin, where Gluck worked as a graduate student in the 1960s. Harlow’s primate lab became famous for his behavioral experiments in maternal deprivation and social isolation of rhesus macaques. Though trained as a behavioral scientist, Gluck finds himself unable to overlook the intense psychological and physical damage these experiments wrought on the macaques. Gluck’s sobering and moving account reveals how in this and other labs, including his own, he came to grapple with the uncomfortable justifications that many researchers were offering for their work. As his sense of conflict grows, we’re right alongside him, developing a deep empathy for the often smart and always vulnerable animals used for these experiments. At a time of unprecedented recognition of the intellectual cognition and emotional intelligence of animals, Voracious Science and Vulnerable Animals is a powerful appeal for our respect and compassion for those creatures who have unwillingly dedicated their lives to science. Through the words of someone who has inflicted pain in the name of science and come to abhor it, it’s important to know what has led this far to progress and where further inroads in animal research ethics are needed.
Immunomodulation in Domestic Food Animals covers the developments in the immunology and regulation of the immune response in domestic food animals. This book is organized into four parts encompassing 12 chapters that describe numerous factors affecting an immune response of animals and the management of these factors for food animal production. Part I provides an overview of the basic concepts of immunomodulation and the rationale for manipulating the immune response in food animals. Part II contains information on immunopotentiation using chemicals and a thorough discussion of adjuvant use. The molecular biology and in vivo use of cytokines in food animals is presented in Part III. Lastly, Part IV discusses physiologically regulated immunomodulation, including nutritional modulation of the immune response and neuroendocrine-immune interactions. This book is of great value to immunologists, microbiologists, and feed scientists and researchers.
Introduction to Laboratory Animal Science and Technology discusses the principles involved in the healthy maintenance of animals in the laboratory or animal house. This book is divided into eight six units of study of the physical requirements of animals, physiological data, and techniques of husbandry, followed by summary data capsules and recommended further reading. After an overview of the laboratory animals, this book goes on dealing with various aspects of animal care, including their accommodation, health care routine, and animal health and hygiene. The next chapters examine the components of animal diet, the biological aspects of animal reproduction, breeding and heredity. The final chapter emphasizes the legal requirements concerning anesthesia, laboratory procedures, and the issue of euthanasia. This book will prove useful to laboratory technicians, students, students, researchers, and the general public who are concerned for animals and their use in laboratory work.
"Animal Nutrition Science introduces the fundamental topics of animal nutrition, in a treatment which deals with terrestrial animals in general. The subjects covered include nutritional ecology and the evolution of feeding styles, nutrients (including minerals, vitamins and water) and their functions, food composition and methods of evaluating foods, mammalian and microbial digestion and the supply of nutrients, control and prediction of food intake, quantitative nutrition and ration formulation, methods of investigating nutritional problems, nutritional genomics, nutrition and the environment, and methods of feed processing and animal responses to processed foods." -- Publisher's description.